Hold’em for Life Oncology Fellowships

Tatianny Paula Araújo Vargas, Sunnybrook Health Sciences Centre
Project: Rare Mutation Melanoma Trial with Encorafenib and Binimetinib

Carly Barron, Princess Margaret Cancer Centre
Project: Cross tumor-comparison of the tumor immune microenvironment, peripheral immune signatures and response to immunotherapy as a novel conceptual model in aerodigestive tumors 

Edward Chen, Lunenfeld-Tanenbaum Research Institute
Project: Immune Modulation in Hippo Pathway Regulated Breast Tumour Microenvironments 

Massimo Di Iorio, Princess Margaret Cancer Centre
Project: Exercise and Rehabilitation for People with Cancer: A Survey of Canadian Oncology Residents’ Knowledge and Awareness of Practice Guidelines

Nely Mercy Díaz Mejía, CBRE Hold'em for Life Fellow, Princess Margaret Cancer Centre
Project: A retrospective review of the use of GCSF for patients with GU receiving chemotherapy during the COVID-19 pandemic and implications for the future

Mitchell Elliot, Princess Margaret Cancer Centre
Project: Acquired pharmacologic vulnerabilities in cyclin dependent kinase 4/6 (CDK4/6) inhibitor-resistant hormone receptor positive breast

Ian Hirsch, Princess Margaret Cancer Centre
Project: Profiling of Cancer of Unknown Primary Site, Melanoma, Adnexal, Skin for Optimizing Immunotherapy

Thomas Kennedy, Sunnybrook Health Sciences Centre
Project: Detection of Circulating Tumour DNA before and after Stereotactic Ablative Radiotherapy for Confirmed and Suspected Early Lung Cancer (SABR-DETECT) 

Colleen Kerrigan, Sunnybrook Health Sciences Centre
Project: Reflex MammaPrint and BluePrint testing on breast cancer core biopsies: Impact on tumor phenotype classification, perceived provider utility, and process implementation

Jethro Kwong, Silvercore Hold'em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Development of an early warning system for non-muscle invasive bladder cancer recurrence and progression using time-series forecasting with artificial intelligence

Diego Malon Gimenez, Princess Margaret Cancer Centre
Project: Incidence, prevalence, risk factors and impact of fatty liver disease in metastatic HR+/HER2− breast cancer patients in first line of treatment with Aromatase Inhibitors and CDK 4/6

Amy Lu, The Hospital for Sick Children
Project: Describing limited English proficiency (LEP) in paediatric oncology

Adi Nitzan-Luques, The Hospital for Sick Children
Project: Translational in vivo modeling to identify therapeutic opportunities for high-risk neuroblastoma

Daniel Palhares, Sunnybrook Health Sciences Centre
Project: Stimulated Microbubble Radiation Enhancement Treatment in Head and Neck Cancer Patients

Jenny Peng, Princess Margaret Cancer Centre
Project: Understanding the gene expression profile of neuroendocrine carcinoma of genitourinary primaries: a pilot study

Erick Saldanha, Princess Margaret Cancer Centre
Project: Use of targeted therapies in patients with advanced thyroid cancer: efficacy and safety outcomes from a real-world genomically profiled cohort

Marie-Philippe Saltiel, Princess Margaret Cancer Centre
Project: Improving the Transition to Practice Curriculym in the Medical Oncology Training Program

Amit Sharma, Lunenfeld-Tanenbaum Research Institute
Project: Deciphering the role of the Formin / Wnt-PCP axis in breast cancer cell motility and Metastasis

Mariska Sie, The Hospital for Sick Children
Project: DNA-damage response targeting and epigenetic priming to overcome radio-resistance in very high-risk medulloblastoma

Ana Veneziani, Princess Margaret Cancer Centre
Project: Phase I Study of Autologous Epithelial Ovarian Cancer (EOC) Cells Containing Lentivirus Engineering Expression of IL-12 

Kevin Wang, Princess Margaret Cancer Centre
Project: Comprehensive genomic, immunologic and metabolomic characterization of the tumour, host, and gut microbiome interaction in hepatocellular carcinoma

Justin Wang, Toronto Western Hospital
Project: Uncovering the epigenetic and transcriptomic biomarkers of response to radiotherapy in meningiomas

Yibo Xue, Lunenfeld-Tanenbaum Research Institute
Project: Studying DNA damage networks in human cancer cells

Rui Miguel Marques Bernardino, Princess Margaret Cancer Centre
Project: Unravelling the potential of extracelular vesicles as biomarkers of intraductal and cribriform prostate cancer

Adom Bondzi-Simpson, Sunnybrook Health Sciences Centre
Project: Integrating equity into quality metrics for colorectal cancer care: an Analysis of wait times for curative-intent surgery

Sanjeev Budhathoki, Lunenfeld-Tanenbaum Research Institute
Project: Development of risk prediction models for early detection and prognosis of aerodigestive cancers

Alberto Hernando Calvo, Princess Margaret Cancer Centre
Project: External validation of the VIGEX gene-expression signature as a novel predictive biomarker for immuno-oncology (IO) treatments

Julian Chavarriaga, Princess Margaret Cancer Centre
Project: miRNAs as potential circulating tumor markers for stratifying and surveilling small testicular masses

Rania Chehade, Sunnybrook Health Sciences Centre
Project: Toward Immunotherapy in breast cancer brain metastases: PD-L1 expression and beyond

Danielle Cuthbert, Princess Margaret Cancer Centre
Project: Process Analysis for the HIMALAYAS Study: Cancer Survivor's Experience with a Supervised Cardio-Oncology Rehabilitation Program

David Cyr, Mount Sinai Hospital
Project: Enhancing Prognostication in Colorectal Cancer: the Role of Clinico-pathologic and Molecular Features Beyond the TNM Staging System

Anirban Das, The Hospital for Sick Children
Project: Gliomas with DNA-replication repair deficiency: How the cell-of-origin, genomic, and epigenetic landscape impact immune-directed therapeutic vulnerability

Ahmed Elmotayam, Lunenfeld-Tanenbaum Research Institute
Project: A New Therapeutic Strategy for Highly Lethal Small Cell Neuroendocrine Cancers 

Abdul Rehman Farook, Princess Margaret Cancer Centre
Project: Cancer cachexia and genotype correlations in Pancreatic Ductal Adenocarcinoma

Jesus Fuentes Antras, Princess Margaret Cancer Centre
Project: Tumor-informed ctDNA dynamics in HR+/HER2- metastatic breast cancer patients receiving first-line CDK4/6 inhibitors

Sofia Genta, Princess Margaret Cancer Centre
Project: CP-101 and Atezolizumab in Patients with Advanced Solid TumorS to INterrogate the Gut Microbiota (CASSIN)

Maru Gete, Mount Sinai Hospital
Project: Molecular Testing of Indeterminate Thyroid Nodules for Informed Surgical Management

Samantha Hershenfeld, Princess Margaret Cancer Centre
Project: Clinico-genetic risk stratification of limited stage follicular lymphoma

Amanda Hird, Sunnybrook Health Sciences Centre
Project: Contemporary Risk of Bone Fractures Among Men with Advanced Prostate Cancer on Androgen Deprivation Therapy

Kyle Juraschka, The Hospital for Sick Children
Project: Harnessing CRISPR to identify drivers of medulloblastoma metastasis

Karineh Kazazian, Princess Margaret Cancer Centre
Project: Indocyanine green (ICG) Guided Sentinel Lymph Node Biopsy in Breast Cancer

Colleen Kerrigan, Sunnybrook Health Sciences Centre
Project: Reflex MammaPrint and BluePrint testing on breast cancer core biopsies: Impact on tumor phenotype classification, perceived provider utility, and process implementation

Ravi Kumar, Princess Margaret Cancer Centre
Project: Characterizing the impact of using novel patient-centered pathology reports in clinical practice

Jethro Kwong, Princess Margaret Cancer Centre
Project: Development of an early warning system for non-muscle invasive bladder cancer recurrence and progression using time-series forecasting with artificial intelligence

Lucy Ma, Princess Margaret Cancer Centre
Project: Next-Generation Sequencing in Advanced Thyroid Cancers: Clinical Application and Impact on Patient Outcomes

Louise McLoughlin, Princess Margaret Cancer Centre
Project: Explainable Artificial Intelligence in the diagnosis of Muscle Invasive Upper Tract Urothelial Carcinoma

Gordon Taylor Moffat, Princess Margaret Cancer Centre
Project: Optimizing the Quality of Surveillance in Patients with Completely Resected Gastroenteropancreatic Neuroendocrine Tumours

Consolacion Molto Valiente, Princess Margaret Cancer Centre
Project: Machine learning to estimate the real-world risk of 3-year disease free survival in patients with residual, triple negative breast cancer after neoadjuvant chemotherapy

Daniel Palhares, Sunnybrook Health Sciences Centre
Project: Pilot Investigation of Ultrasound Cell Death Imaging and Spectroscopy as Early Indicators of Response to Radiation Treatment in Prostate Cancer

Sabrina Piedimonte, Princess Margaret Cancer Centre
Project: Predicting Response to Neoadjuvant Chemotherapy in Advanced Ovarian Cancer Using the Rate of Elimination of CA-125 (KELIM Score) and Chemo-Response Score

Nikhil Raghuram, The Hospital for Sick Children
Project: Targeting EZH2 in EBTs: Role of epigenetic modifiers in modulating pluripotency

Gabriel Revon-Riviere, The Hospital for Sick Children
Project: Characterization of MUC16/CA125 expression in pediatric in pediatric soft-tissue sarcomas and pilot study of a first-in-class MUC16/CA125 T-cell engager bispecific antibody

Enrique Sanz Garcia, Princess Margaret Cancer Centre
Project: Study of circulating tumor DNA (ctDNA) kinetics in immuno-oncology (IO-KIN)

Alina Selega, Lunenfeld-Tanenbaum Research Institute
Project: Detecting epithelial-mesenchymal transition states in highly multiplexed imaging data

Mariska Sie, The Hospital for Sick Children
Project: Epigenetic Priming to Overcome Radio-Resistance in Very High-Risk Medulloblastoma

Pavlina Spiliopoulou, Princess Margaret Cancer Centre
Project: Immune Response to COVID-19 Vaccine in immunotherapy (IO) and non-IO Treated Cancer Patients (VIVACIOUS)

Henry Miew Hoon Su, Toronto General Hospital
Project: Age Related Clonal Hematopoiesis and Atherosclerotic Cardiovascular Disease in Cancer Survivors

Michael S. Taccone, The Hospital for Sick Children
Project: Mitochondrial Fission: Targeting the Achilles’ Heel of Glioblastoma

Raj Vikesh Tiwari, Princess Margaret Cancer Centre
Project: Free/Total PSA ratio as a biomarker for PSMA PET positivity in patients with biochemical recurrence post prostatectomy

Randy Van Ommeren, The Hospital for Sick Children
Project: Characterization of the metabolic drivers of grp3 medulloblastoma metastasis

Richard Walker, Sunnybrook Health Sciences Centre
Project: Learning Curves and Volume-Outcome Relationships in Robot-Assisted Surgical Oncology

Irene Xie, Princess Margaret Cancer Centre
Project: Identifying molecular vulnerabilities in pancreatic ductal adenocarcinoma

Jeffrey Zuccato, Princess Margaret Cancer Centre
Project: Lung adenocarcinoma brain metastasis prediction and non-invasive diagnosis using methylation signatures in tissue and plasma

Marie Alt, Mount Sinai Hospital
Project: Optimizing Sexual Health and Emotional Well-Being got Breast Cancer Patients and Survivors

Federico Carini, Mount Sinai Hospital
Project: Venous thromboembolism in hematologic malignancy and hematopoietic cell transplant patients

Douglas Cheung, Princess Margaret Cancer Centre
Project: Seeing Clearly: A Decision Analysis of MRI, PSMA PET/CT, and Biomarker Testing in Early Prostate Cancer Detection

Sarah Cohen-Gogo, The Hospital for Sick Children
Project: PICTURE: PARP Inhibitors and Chemotherapy for patients harbouring TUmours with homologous REcombination repair deficiency: a phase II pilot study

David Cyr, Mount Sinai Hospital
Project: Clinicopathologic and Molecular Predictors of Outcomes Following Salvage Surgery for Locally Recurrent Rectal Cancer 

Alexandra Desnoyers, Princess Margaret Cancer Centre
Project: Fragility Index of Approved Cancer Drugs 

Grace Egan, Princess Margaret Cancer Centre
Project: Nuclear Hexokinase 2: Mechanism of Regulating Stemness in Acute Myeloid Leukemia

Robert Grant, Princess Margaret Cancer Centre
Project: Predicting Outcomes in Pancreatic Cancer from Clinical and Genomic Data using Machine Learning

Alexander Gregor, Toronto General Hospital
Project: Enhancing sentinel lymph node mapping in lung cancer surgery using a novel liposome-based dual-modality nanoparticle 

Keegan Guidolin, Princess Margaret Cancer Centre
Project: Porphysomes for the intraoperative visualization of colorectal lymph node metastases

Dumas Guillaume, Mount Sinai Hospital
Project: The Impact of Critical Illness on Oncology Care Following Critical Care Survival

Fyeza Hasan, The Hospital for Sick Children
Project: Children with Cancer as Participants in End-of-life-Research

Kyle Juraschka, The Hospital for Sick Children
Project: Harnessing CRISPR to identify drivers of medulloblastoma metastasis 

Kristen McAlpine, Princess Margaret Cancer Centre
Project: Comparison of OpeN VErsus RoboTic (CONVERT) Partial Nephrectomy Trial- a feasibility randomized control trial

Nick Meti, Princess Margaret Cancer Centre
Project: Machine Learning to estimate risk of 3-year disease-free survival in patients with residual, HER2-positive breast cancer after neoadjuvant chemotherapy and HER2- targeted therapy.

Randy Van Ommeren, The Hospital for Sick Children
Project: Characterization of the metabolic drivers of grp3 medulloblastoma metastasis

Michael Taccone, The Hospital for Sick Children
Project: Mitochondrial Fission: Targeting the Achilles' Heel of Glioblastoma 

Abi Vijenthira, Princess Margaret Cancer Centre
Project: Application of the Generalizable Frailty Index using population-based health administrative data in older patients with diffuse large B-cell lymphoma (DLBCL), with further sensitivity analyses using a smaller cohort with detailed pathologic and cancer-specific data 

Irene Xie, Princess Margaret Cancer Centre
Project: Identifying molecular vulnerabilities in pancreatic cancer 

Marie Alt, Mount Sinai Hospital
Project: Optimizing Sexual Health and Emotional Well-Being got Breast Cancer Patients and Survivors

Zubair Bayat, Mount Sinai Hospital
Project: Toward Streamlining Colon Cancer Care

Oscar Calvillo, Toronto General Hospital
Project: Characterizing Heart And Mind health Post-chemotherapy In Women with early-stage breast cancer (CHAMPION)

Alberto Hernando Calvo, Princess Margaret Cancer Centre
Project: External validation of the VIGEX gene-expression signature as a novel predictive biomarker for immuneoncology (IO) treatments

Hanbo Chen, Sunnybrook Health Sciences Centre
Project: Towards a Better Therapeutic Ratio: The Role of Magnetic Resonance-Linear Accelerator (MR-Linac) in Radiotherapy

Douglas Cheung, Princess Margaret Cancer Centre
Project: Seeing Clearly: A Decision Analysis of MRI, PSMA PET/CT, and Biomarker Testing in Early Prostate Cancer Detection

Sarah Cohen-Gogo, The Hospital for Sick Children
Project: PICTURE: PARP Inhibitors and Chemotherapy for patients harbouring TUmours with homologous REcombination repair deficiency: a phase II pilot study

David Cyr, Mount Sinai Hospital
Project: Clinicopathologic and Molecular Predictors of Outcomes Following Salvage Surgery for Locally Recurrent Rectal Cancer 

Alexandra Desnoyers, Princess Margaret Cancer Centre
Project: Fragility Index of Approved Cancer Drugs 

Lawson Eng, Princess Margaret Cancer Centre
Project: ONCO-GEMINI: Oncology Continuum General Medicine Inpatient Initiative 

Carrillo Estrada, Mount Sinai Hospital
Project: Cardiac Outcomes in Pregnant Cancer Survivors: A Prospective Cohort Study

Sofia Genta, Princess Margaret Cancer Centre
Project: Immune Resistance Interrogation Study (IRIS): evaluating genomic, transcriptomic, epigenetic, immunophenotypic and radiomic profiles associated with primary and acquired resistance to PD1/PD-L1 targeting agents.

Rachel Glicksman, Sunnybrook Health Sciences Centre
Project: Early surrogate measures and predictors of outcome for intermediate risk prostate cancer patients treated with ablative therapies

Robert Grant, SmartCentres Hold’em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Predicting Outcomes in Pancreatic Cancer from Clinical and Genomic Data using Machine Learning

Alexander Gregor, Toronto General Hospital 
Project: Enhancing sentinel lymph node mapping in lung cancer surgery using a novel liposome-based dual-modality nanoparticle 

Keegan Guidolin, CMCC/Atrium Hold’em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Porphysomes for the intraoperative visualization of colorectal lymph node metastases

Paulo Kayano, Princess Margaret Cancer Centre
Project: Impact of Proton Pump Inhibitors on prostate cancer diagnosis and outcomes 

Rachel Kim, CMCC/Atrium Hold’em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Characterization of endometrioid carcinoma of the endometrium: molecular subtype assignment to infirm treatment decisions and improve outcomes 

Tristan Knight, RBC Hold'em for Life Oncology Fellow, The Hospital for Sick Children
Project: Re-envisioning the autologous hematopoietic stem cell transplant as immunotherapy

Eyal Lebel, Princess Margaret Cancer Centre
Project: Clinical applications of free DNA in Multiple Myeloma 

Jerry Ku, Sunnybrook Health Sciences Centre
Project: Adjuvant 5-aminolevulinic acid-based intraoperative photodynamic therapy of glioblastoma multiforme: A prospective pilot study

Bryan Li, The Hospital for Sick Children
Project: High-throughput drug screening and development of in vivo drug models for pineoblastoma

Shelly Luu, BMO Hold'em for Life Oncology Fellow, Mount Sinai Hospital
Project: Investigation of the Polo-like Kinas 4 Interactome as a Novel Therapeutic Target in Gastric Cancer

Wanda Marini, Katie Hoffman Hold’em for Life Oncology Fellow, Mount Sinai Hospital
Project: The Role of Hedgehog Signaling in Basal-Like Breast Cancer and the Tumor Microenvironment

Kristen McAlpine, Princess Margaret Cancer Centre
Project: Establishing national benchmarks and quality improvement priorities for the surgical care of kidney cancer patients in Canada

Michelle Nadler, Dream Hold’em for Life Oncology Fellow, Women's College Hospital
Project: What are the determinants of breast cancer screening practices for women aged 40-49?

Farshad Nassiri, Toronto Western Hospital
Project: Establishing the utility of a novel plasma-based biomarker to non invasively prognosticate meningiomas

Christopher Noel, Levinsky Waratah Hold’em for Life Oncology Fellowship, Sunnybrook Health Sciences Centre
Project: Symptom Burden as a Predictor of Emergency Room Visits and Unplanned Hospitalizations in Patients with Head and Neck Cancer 

Sarah Picardo, Princess Margaret Cancer Centre
Project: Evaluation of the tumour-adjacent microbiota in patients with metastatic genitourinary (GU) cANcers: the URinary and fecal microBiome (URBAN)

Khaled Ramadan, Silverberg Hold’em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Photodynamic Therapy during in vivo lung perfusion for treatment of lung metastases 

April Rose, Princess Margaret Cancer Centre
Project: Characterizing mechanisms of response and resistance to binimetinib and encorafenib in advanced cancers with non- V600E BRAF mutations: correlative analyses of the BEAVER trail 

Abdulazeez Salawu, Mount Sinai Hospital
Project: Circulating Tumor DNA Detection in Soft Tissue Sarcoma (DNATSAR)

Carlos Stecca, Princess Margaret Cancer Centre
Project: Feasibly Integrating Epigenomic and Genomic Liquid Biopsy Biomarkers  

Michael Taccone, The Hospital for Sick Children
Project: Mitochondrial Fission: Targeting the Achilles' Heel of Glioblastoma 

Abi Vijenthira, The Gerald Schwartz & Heather Reisman Foundation Hold'em For Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Application of the Generalizable Frailty Index using population-based health administrative data in older patients with diffuse large B-cell lymphoma (DLBCL), with further sensitivity analyses using a smaller cohort with detailed pathologic and cancer-specific data 

Mathew Voisin, Toronto Western Hospital
Project: Liquid biopsy of gliomas by absolute quantification of IDH mutation

Pei Jye Voon, Princess Margaret Cancer Centre
Project: Measurement of psychometric properties of the Functional Assessment of Cancer Therapy – Immune Checkpoint Modulators (FACT-ICM) health related quality of life tool in patients treated with durvalumab and oleclumab in various solid tumors

Geoff Watson, Princess Margaret Cancer Centre
Project: Evaluating the Integrative Role of Regulatory T Cells, Myeloid-Derived Suppressor Cells, Inflammatory Cytokines and Neutrophil-Lymphocyte Ratio as Biomarkers of Response and Toxicity in Patients with Advanced Stage Cancer Treated with Pembrolizumab 

Irene Xie, CIBC Capital Markets Hold’em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Identifying molecular vulnerabilities in pancreatic cancer 

Zsolt Zador, The Hospital for Sick Children
Project: Exploring the spectrum of cell identities and treatment vulnerabilities in K27M pediatric gliomas

Zubair Bayat, Mount Sinai Hospital
Project: Toward Streamlining Colon Cancer Care

Oscar Calvillo, Toronto General Hospital
Project: Characterizing Heart And Mind health Post-chemotherapy In Women with early-stage breast cancer (CHAMPION)

Vaibhav Gupta, Sunnybrook Health Sciences Centre
Project: Development and external validation of a personalized model to predict survival in esophageal cancer patients 

Otto Hemminki, SmartCentres Hold’em for Life Oncology Fellow, Mount Sinai Hospital
Project: Transforming care for high-risk muscle-invasive bladder cancer using fast-tracked new MRI techniques and radiomics to decrease time to cystectomy 

Paulo Kayano, Princess Margaret Cancer Centre
Project: Impact of Proton Pump Inhibitors on prostate cancer diagnosis and outcomes 

Shelly Luu, BMO Hold'em for Life Oncology Fellow, Mount Sinai Hospital
Project: Investigation of the Polo-like Kinas 4 Interactome as a Novel Therapeutic Target in Gastric Cancer

Wanda Marini, Katie Hoffman Hold’em for Life Oncology Fellow, Mount Sinai Hospital
Project: The Role of Hedgehog Signaling in Basal-Like Breast Cancer and the Tumor Microenvironment

Dave Mealiea, Mount Sinai Hospital
Project: Investigation and Design of Oncolytic Vaccinia Virus-Based Therapies in Colorectal Cancer

Ying Meng, Sunnybrook Health Sciences Centre
Project: Liquid biopsy of brain tumours using MR-guided focused ultrasound-induced blood-brain barrier disruption 

Michelle Nadler, Dream Hold’em for Life Oncology Fellow, Women's College Hospital
Project: What are the determinants of breast cancer screening practices for women aged 40-49?

Gregory Nason, CentreCourt Hold’em for Life Oncology Fellow, Princess Margaret Cancer Centre
Project: Comparison of OpeN VErsus RoboTic (CONVERT) Partial Nephrectomy Trial- a feasibility randomized control trial

Farshad Nassiri, Toronto Western Hospital
Project: Establishing the utility of a novel plasma-based biomarker to non invasively prognosticate meningiomas 

Sarah Picardo, Princess Margaret Cancer Centre
Project: Evaluation of the tumour-adjacent microbiota in patients with metastatic genitourinary (GU) cANcers: the URinary and fecal microBiome (URBAN)

Jenna Spring, Mount Sinai Hospital
Project: Early Advance Care Planning in Hematologic Malignancies and Hematopoietic Stem Cell Transplants: A Pre-Post Pilot Study 

Carlos Stecca, Princess Margaret Cancer Centre
Project: Feasibly Integrating Epigenomic and Genomic Liquid Biopsy Biomarkers